Searchable abstracts of presentations at key conferences in endocrinology

ea0063p356 | Thyroid 1 | ECE2019

Relationship among T- and B-lymphocytes of the peripheral blood and thyroid tissue in patients with Graves’ disease

Dudina Margarita A , Savchenko Andrey A , Dogadin Sergey A , Borisov Alexandr G , Kudryavcev Igor V , Moshev Anton V , Man'kovsky Vladimir A

The exact pathogenesis and causative interaction between T- and B-lymphocytes in peripheral blood and thyroid gland immune-mediated mechanisms of Graves disease (GD) are still unknown. Detailed knowledge about lymphocyte subpopulation composition in peripheral blood and thyroid tissue will therefore enhance our understanding of the pathogenesis of GD and might support the development of new immunomodulatory treatment approaches. Aim: to study the relationship between helper- (...